I am five letter word that is under you.
If you remove my 1st letter, then I am over you.
If you remove my 1st and 2nd letters then I am all around you.
Take number 1000 and then add 20 to it.
Now add 1000 one more time.
Now add 30.
Now add 1000 one more time.
Now add 40.
Now add 1000 one more time.
Now add 10.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.