Today is John's birthday.
A year ago, John had five candles and he lit all the candles except the one at the last.
Now he is going to light all the candles.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.