Find the next number in the sequence

1, 2, 6, 21, 88, __?

Two natural numbers have a sum of less than 100 and are greater than one.

John knows the product of the numbers and Jacob knows the sum of numbers.

The following conversation takes place between them:
John: 'I am not aware of those numbers.'
Jacob: 'I knew you wouldn't be. I am not aware myself.'
John: 'Now I know them!'
Jacob: 'Now I know them, too!'

What are the two numbers?

A word I know,
Six letters contain,
Subtract just one,
And twelve is what remains.

What are the next two letters in the following series and why?
W A T N T L I T F S _ _

*Hint: Check Puzzle Title

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Which word does the below Plexor means ?

John was a very careless driver, so his owner Jacob gave him an offer that he will get an incentive of Rs.30 for every bottle box he delivered without breaking it and he will be charged Rs.90 for every bottle box he broke. Jacob gave John 100 bottles-box to deliver. After delivery, Jacob paid John Rs.2400. How many bottles-box did John break?