Find the next number in the sequence

1, 2, 6, 21, 88, __?

What brings you down but never up?

How can you leave a room with two legs and return with six legs?

John was a very careless driver, so his owner Jacob gave him an offer that he will get an incentive of Rs.30 for every bottle box he delivered without breaking it and he will be charged Rs.90 for every bottle box he broke. Jacob gave John 100 bottles-box to deliver. After delivery, Jacob paid John Rs.2400. How many bottles-box did John break?

Three fair coins are tossed in the air and they land with heads up. Can you calculate the chances that when they are tossed again, two coins will again land with heads up?

A crime was committed at baker street. Ibrahim Dakota who was shot in the stomach was the main suspect. Sherlock questioned the suspect. The conversation started as:
Sherlock: What's your story, Ibrahim?
Ibrahim: I was walking around baker street and suddenly a man from the back shot me. I ran as fast as I could to save my life".
Sherlock: That is enough (and ask the police to arrest him).

Why does Sherlock think he is the murderer?

In particular commonwealth games, a female participant won silver and gold medals for a single event.

How can this be possible?

A girl was standing near the window thinking something. All of a sudden she decides something and throws something out of the window. She dies very soon after throwing it. She was perfectly healthy and had no disease or allergy. No one killed her and she did not commit suicide.

Can you think of any possible explanation that is logical as well for what happened there?

If you drop a 15 kg iron bar and a 5 kg bag of cotton from a height of 50 meters which will reach the ground first?

Can you identify the direction in which this bus is moving; left or right?

Hint: The bus is moving on the roads of London.