You have to put a letter on the following to make it a meaningful word. The only challenge is that you can't use 'E'.

S E Q U E N C _

In a contest, four fruits (an apple, a banana, an orange, and a pear) have been placed in four closed boxes (one fruit per box). People may guess which fruit is in which box. 123 people participate in the contest. When the boxes are opened, it turns out that 43 people have guessed none of the fruits correctly, 39 people have guessed one fruit correctly, and 31 people have guessed two fruits correctly.
How many people have guessed three fruits correctly, and how many people have guessed four fruits correctly

John and his wife were living in a rural place. On a particular day, John's wife fell ill and he called the local doctor. When the doctor picked up, he said, "Doctor, my wife is ill. She might have appendicitis."

"This can't be possible! I took out her appendix two years ago myself," the doctor explained.

When diagnosed, John's wife was found to have appendicitis. How can this be possible?

Andrew’s doctor gives him three pills and tells him to take one every half hour. How much time will have passed by the time Andrew’s taken all three pills?

A girl was sitting in her hotel room when she heard a knock on the door. She opened the door and found that a man was standing outside.
The man said, "Oh! I am really sorry, I thought this was my room."
He then walked through the corridor to the elevator. The girl did not know the man. She closed her door and called security asking them to apprehend the man.
What made her suspicious of that man? He might have been genuinely mistaken.

A king sentenced a man to the death sentence for some crime he had committed. Known for his kindness, the king told the culprit that he had a choice to die in a way he decides.

The culprit was clever and said something that saved him from death. What method do you think he must have chosen for his death?

A man who was outside in the rain without an umbrella or hat didn’t get a single hair on his head wet. Why?

Only one color, but not one size,
Stuck at the bottom, yet easily flies.
Present in sun, but not in rain,
Doing no harm, and feeling no pain.
What is it?

A deaf and mute man goes to the train station. Tickets for the train are 50 cents each. The man goes to the ticket booth and hands the man inside just a dollar. The man in the booth hands him two tickets.

How did the man in the booth know to give him two tickets without even looking at him?

These types of puzzles are known as charades. What you have to do is to find two words that are referred to in the first stanza and the second stanza and put them together to form the third word in the third stanza.

Just for example, if my first refers to 'off' and my second refers to 'ice', then my whole will be the 'office'.

My first is present - future's past -
A time in which your lot is cast.

My second is my first of space
Defining people's present place.

My whole describes a lack of site -
A place without length, breadth, or height.