I am first found in caves, now prolific online; I am a depiction, a drawing, a symbol, or sign. I will convey whichever mood you could wish; or for that matter, a fist, flask, or fish. What am I?
It's pretty hard to give up.
If you remove a part of it, you will be left with a bit.
Even if you remove another part, the bit still remains.
Remove one more and it still remains.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.