Relationship in Numbers and Letters

If we tell you that there is a relation between the numbers and letters in the given figure, can you analyze it and find the missing letter in the last box?

Relationship in Numbers and Letters




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Amazing Facts

No Solution

In 2007, a puzzle was released and $2 million prizes were offered for the first complete solution. The competition ended at noon on 31 December 2010, with no solution being found. Wiki