A 3 digit number is such that it's unit digit is equal to the product of the other two digits which are prime. Also, the difference between it's reverse and itself is 396.
In the image below, you can see two glasses and two matchsticks.You need to move four matchsticks in such a manner that the crosses come inside the glasses. Note: you cannot move the crossed.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.