There is a box in which distinct numbered balls have been kept. You have to pick two balls randomly from the lot.
If someone is offering you a 2 to 1 odds that the numbers will be relatively prime, for example
If the balls you picked had the numbers 6 and 13, you lose $1.
If the balls you picked had the numbers 5 and 25, you win $2.
You are in a room that has three switches and a closed door. The switches control three light bulbs on the other side of the door. Once you open the door, you may never touch the switches again. How can you definitively tell which switch is connected to each of the light bulbs?
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.