I have nine bottles of wine and one of the nine bottles is poisoned.
I need to find the poisoned bottle with two facts
(1) Poison is deadly, only a sip will cost death
(2) I have two mice to do so.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.