What does this rebus riddle means ?

Replace the question mark with the number below given a simple math problem.

What makes this number unique: 8,549,176,320?

A high school has a strange principal. On the first day, he has his students perform an odd opening day ceremony:

There are one thousand lockers and one thousand students in the school. The principal asks the first student to go to every locker and open it. Then he has the second student go to every second locker and close it. The third goes to every third locker and, if it is closed, he opens it, and if it is open, he closes it. The fourth student does this to every fourth locker, and so on. After the process is completed with the thousandth student, how many lockers are open?

Replace the (?) with the correct mathematical signs to make the expression equal to 59.

18 ? 12 ? 4 ? 5 = 59

Mr. Buttons was all set to go to the village of Buttonland to meet his friend. So, he packed his bags and left for the village at 5 in the morning. Upon travelling on a road for miles, he came across a point where the road diverged into two. He was confused on which road to take. He gazed around and he saw two owls sitting on a branch. He thought he could ask for directions for the village from the two owls. So he went to the tree. There he saw a sign which read, "One owl always lies, and one is always truthful. They both fly away if you ask them more than 1 question."
Mr. Buttons was caught in the dilemma of what to ask? And from which owl to ask, since he only had one question. What should Mr. Buttons ask?

A girl was standing near the window thinking something. All of a sudden she decides something and throws something out of the window. She dies very soon after throwing it. She was perfectly healthy and had no disease or allergy. No one killed her and she did not commit suicide.

Can you think of any possible explanation that is logical as well for what happened there?

Two natural numbers have a sum of less than 100 and are greater than one.

John knows the product of the numbers and Jacob knows the sum of numbers.

The following conversation takes place between them:
John: 'I am not aware of those numbers.'
Jacob: 'I knew you wouldn't be. I am not aware myself.'
John: 'Now I know them!'
Jacob: 'Now I know them, too!'

What are the two numbers?

What does an Island and the letter T have in common?

A farmer went to a market and bought a wolf, a goat, and a cabbage. On his way home, the farmer came to the bank of a river and rented a boat. But crossing the river by boat, the farmer could carry only himself and a single one of his purchases: the wolf, the goat, or the cabbage. If left unattended together, the wolf would eat the goat, or the goat would eat the cabbage. The farmer’s challenge was to carry himself and his purchases to the far bank of the river, leaving each purchase intact. How did he do it?