Can you find out which number multiplied by itself will give the output as 12345678987654321?

John and his wife were living in a rural place. On a particular day, John's wife fell ill and he called the local doctor. When the doctor picked up, he said, "Doctor, my wife is ill. She might have appendicitis."

"This can't be possible! I took out her appendix two years ago myself," the doctor explained.

When diagnosed, John's wife was found to have appendicitis. How can this be possible?

What is the fastest way to double your money?

In order to complete the racing competition, the Mexico racetrack has to submit its top and the most famous three horses to win the competition. Due to an electrical storm, all the records are cleared and no one knows which horse holds the record. They all look identical and it becomes even more difficult to differentiate the horses. There are 25 horses in the Mexico racetrack. But there can be only five horses at a time on the track. What will the least number of races that can be conducted to find out the three fastest horses?

There are 20 people in an empty, square room. Each person has full sight of the entire room and everyone in it without turning his head or body, or moving in any way (other than the eyes). Where can you place an apple so that all but one person can see it?

A man says, "Brothers and sisters, have I none, but that man's father is my father's son." Who is that man?

The following "Brain Bat" means Slow Down.
S
L
O
W

Using the same logic, can you tell us what does the following Brain Bat means ?
E
V
I
G

It has five wheels, though often think four, You cannot use it without that one more, You can put things in it, you can strap things on top, You can't find it in the market, but you can still go shop. What is it?

Here is what you have to do. You have to throw a ball as hard as you can but it must return back to you even if it does not bounce at anything. Also, you have nothing attached to the ball. There is no one on the other end to catch that ball and throw it back at you.

How will you do it?

I have nine bottles of wine and one of the nine bottles is poisoned.
I need to find the poisoned bottle with two facts
(1) Poison is deadly, only a sip will cost death
(2) I have two mice to do so.

How should I do it?