You have to put a letter on the following to make it a meaningful word. The only challenge is that you can't use 'E'.

S E Q U E N C _

Replace the question mark with the number below given a simple math problem.

I drive at an average speed of 30 miles per hour to the railroad station each morning and catch my train. On a particular morning, there was a lot of traffic and at the halfway point, I had averaged only 15 miles per hour. How fast must I drive for the rest of the way to catch my train?

Begin with a word, five letters to my name,
Remove the first and last but I am the same
Take out my middle and still, I remain.
What word am I?

In a contest, four fruits (an apple, a banana, an orange, and a pear) have been placed in four closed boxes (one fruit per box). People may guess which fruit is in which box. 123 people participate in the contest. When the boxes are opened, it turns out that 43 people have guessed none of the fruits correctly, 39 people have guessed one fruit correctly, and 31 people have guessed two fruits correctly.
How many people have guessed three fruits correctly, and how many people have guessed four fruits correctly

We have arranged an array of numbers below. What you have to do is use any kind of mathematical symbol you know excluding any symbol that contains a number like cube root. You can use any amount of symbols but you have to come up with a valid equation for all of them.

0 0 0 = 6
1 1 1 = 6
2 + 2 + 2 = 6
3 3 3 = 6
4 4 4 = 6
5 5 5 = 6
6 6 6 = 6
7 7 7 = 6
8 8 8 = 6
9 9 9 = 6

On her drawing table, Sayna lit 12 coloured candles. A few seconds later she blew two candles off.

How many candles Sayna have at the end?

A game is being played where eight players can last for thirty-five minutes. Six substitutes alternate with each player in this game. Thus, all players are on the pitch for the same amount of time including the substitutes.

For how long is each player on the pitch?

John enters a small room. The Door Closes.
When the door opens, John is in a larger room.

Explain?

You are given a cube that is made with the help of 10x10x10 smaller cubes summing up to a total of 1000 smaller cubes. You are asked to take off one layer of the cubes.
How many remain now?