A 3 digit number is such that it's unit digit is equal to the product of the other two digits which are prime. Also, the difference between it's reverse and itself is 396.
You are given a cube that is made with the help of 10x10x10 smaller cubes summing up to a total of 1000 smaller cubes. You are asked to take off one layer of the cubes.
How many remain now?
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.
