See the given image carefully. What you have to do is move the blue checkers in the position of the black checkers and vice versa. You are only allowed to move the checker to an adjacent empty space. Do it in the least possible moves.
In 2011, people playing Foldit, an online puzzle game about protein folding, resolved the structure of an enzyme that causes an Aids-like disease in monkeys. Researchers had been working on the problem for 13 years. The gamers solved it in three weeks.